Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Inotersen: First Global Approval.
|
30120737 |
2018 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
In this study, we measured the frequency of unrecognized wild-type transthyretin deposition in patients with idiopathic carpal tunnel syndrome.
|
21733562 |
2011 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
CTD_human |
|
|
|
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Taken together with reports of patients with the same TTR variant, Val 107 TTR mutation is probably associated with a clinical phenotype characterized by carpal tunnel syndrome, cardiomyopathy, bulbar palsy and dysphonia.
|
12039669 |
2002 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
We induced myocardial infarction (MI) in micromini-pigs (15-25 kg) and transplanted the L-CTSs (Tx) 2 weeks after MI induction (4 sheets/recipient) under immunosuppression (Tx: n = 5, Sham: n = 5).
|
30071102 |
2018 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Our findings account for clinical heterogeneity of TTR-derived amyloidosis, and suggest the importance of substitution itself for deposits of amyloid in CTS.
|
8309582 |
1994 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Although concomitant lesions in the ulnar nerve entrapment site at the wrist cannot be excluded, these findings indicate that CTS is not the sole distinctive feature in the majority of FAP ATTR Val30Met patients.
|
19626479 |
2009 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
A novel transthyretin Lys70Glu (p.Lys90Glu) mutation presenting with vitreous amyloidosis and carpal tunnel syndrome.
|
26828956 |
2016 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
Seven factors predict a delayed diagnosis including ATTR amyloid type (ratio =2.17, 95% CI 1.31-3.59), having carpal tunnel syndrome (2.13, CI 1.49-3.03) and age <70 at first symptom (1.85, CI 1.30-2.61).
|
30169971 |
2018 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Familial amyloidotic polyneuropathy presenting with carpal tunnel syndrome and a new transthyretin mutation, asparagine 70.
|
1436517 |
1992 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
A review of the scientific literature indicated that neither the scientific basis nor the population validity of the PMP22 or TTR tests for carpal tunnel syndrome were adequately established before use on railroad track workers in 2000.
|
12802212 |
2003 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Inotersen: First Global Approval.
|
30120737 |
2018 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
Amyloid deposition of wild-type TTR (WT-ATTR) has been found in transverse carpal ligament (TCL) in idiopathic CTS.
|
28413892 |
2017 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Nodular cutaneous amyloidosis and carpal tunnel syndrome due to the amyloidogenic transthyretin His 114 variant.
|
11409031 |
2001 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Our findings account for clinical heterogeneity of TTR-derived amyloidosis, and suggest the importance of substitution itself for deposits of amyloid in CTS.
|
8309582 |
1994 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Transthyretin Tyr69-to-Ile mutation (double-nucleotide substitution in codon 69) in a Japanese familial amyloidosis patient with cardiomyopathy and carpal tunnel syndrome.
|
12762138 |
2003 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
LHGDN |
A Swedish family with the rare Phe33Leu transthyretin mutation.
|
16194875 |
2005 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
Establishing and validating the fluorescent amyloid ligand h-FTAA (heptamer formyl thiophene acetic acid) to identify transthyretin amyloid deposits in carpal tunnel syndrome.
|
28434259 |
2017 |
Carpal Tunnel Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
ATTR amyloid in the carpal tunnel ligament is frequently of wildtype transthyretin origin.
|
23244293 |
2013 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
SSCP and direct sequencing of exons 2, 3, and 4 of the TTR gene were done on DNA from the proband and his brother who had had CTS.
|
12762139 |
2003 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Although CTS associated with TTR amyloidosis has been known as an initial symptom in some patients with ATTR non-Val30Met FAP and those with senile systemic amyloidosis, this is the first report of ATTR Val30Met FAP patients starting with upper limb neuropathy including CTS-like symptoms.
|
20132088 |
2010 |
Carpal Tunnel Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Single-strand conformation polymorphism (SSCP) was analyzed to detect a mutation in the transthyretin (TTR) gene from the mother and son showing polyneuropathy with carpal tunnel syndrome.
|
1656975 |
1991 |
Carpal Tunnel Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Both subscales of the Boston Carpal Tunnel Questionnaire (Symptom Severity Scale and Functional Status Scale) correlated significantly with the CTS-6 and EuroQol 5 Dimensions, indicating good construct validity.
|
31132964 |
2019 |